BDBM50104348 4-[2-Biphenyl-4-yl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL85741

SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=IVQRDNQHHJAUCS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50104348   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104348(4-[2-Biphenyl-4-yl-5-(4-fluoro-phenyl)-3H-imidazol...)
Affinity DataIC50: 300nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50104348(4-[2-Biphenyl-4-yl-5-(4-fluoro-phenyl)-3H-imidazol...)
Affinity DataIC50: 301nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article

TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50104348(4-[2-Biphenyl-4-yl-5-(4-fluoro-phenyl)-3H-imidazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed