BDBM50104356 4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-pyridine::CHEMBL416169

SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1

InChI Key InChIKey=AZBHFSLUTGHEPH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50104356   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article

TargetMitogen-activated protein kinase 14(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: 154nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: 130nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed