BDBM50104376 4-[5-(4-Fluoro-phenyl)-2-phenethyl-3H-imidazol-4-yl]-pyridine::CHEMBL87858

SMILES Fc1ccc(cc1)-c1[nH]c(CCc2ccccc2)nc1-c1ccncc1

InChI Key InChIKey=KZLCRRAGBNSUBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50104376   

TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50104376(4-[5-(4-Fluoro-phenyl)-2-phenethyl-3H-imidazol-4-y...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104376(4-[5-(4-Fluoro-phenyl)-2-phenethyl-3H-imidazol-4-y...)
Affinity DataIC50: 130nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50104376(4-[5-(4-Fluoro-phenyl)-2-phenethyl-3H-imidazol-4-y...)
Affinity DataIC50: 690nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed