BDBM50104517 4-[5-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2-yl]-meth-(Z)-ylidene]-3,6-dioxo-piperazin-(2Z)-ylidenemethyl]-benzonitrile::CHEMBL86980

SMILES CN(C)CCSc1ccc(\C=c2/[nH]c(=O)\c(=C\c3ccc(cc3)C#N)[nH]c2=O)s1

InChI Key InChIKey=JHAXZQDKCAFBCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104517   

TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandPNGBDBM50104517(4-[5-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed