BDBM50104528 4-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetylamino}-butyl)-isoxazol-5-yl]-butyric acid::CHEMBL89056

SMILES CC(C)C[C@H](NC(=O)Cc1ccc(NC(=O)Nc2ccccc2C)cc1)c1cc(CCCC(O)=O)on1

InChI Key InChIKey=MTTJAKXIRMNNOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104528   

TargetIntegrin alpha-4/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50104528(4-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50104528(4-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed