BDBM50104623 CHEMBL3593549

SMILES CCCC[C@H]1CN([C@H](CN2CCC[C@H]2CN2[C@H](Cc3ccc4ccccc4c3)CNC(=O)C2=O)Cc2ccc(O)cc2)C(=O)C(=O)N1CCC12CC3CC(CC(C3)C1)C2

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50104623   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104623(CHEMBL3593549)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104623(CHEMBL3593549)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP8 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104623(CHEMBL3593549)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP9 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104623(CHEMBL3593549)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104623(CHEMBL3593549)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104623(CHEMBL3593549)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed