BDBM50104706 CHEMBL111179::N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-2-phenylmethanesulfonylamino-propionamide

SMILES C[C@H](NS(=O)(=O)Cc1ccccc1)C(=O)NC1=NN=C(CS1)c1ccc(Cl)cc1

InChI Key InChIKey=GINBTQGVSPUJLE-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50104706   

TargetMatrix metalloproteinase-9(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  40nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  90nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  120nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  180nMAssay Description:In vitro inhibitory activity against the ectodomain of the human matrix metalloproteinase-14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  190nMAssay Description:In vitro inhibitory activity against the catalytic domain of human matrix metalloprotease-14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  360nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104706(N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-...)
Affinity DataKi:  480nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed