BDBM50104845 CHEMBL113369::N-[2-(4-Fluoro-phenyl)-cyclopropanecarbonyl]-guanidine

SMILES NC(=N)NC(=O)[C@H]1C[C@@H]1c1ccc(F)cc1

InChI Key InChIKey=YNOFKCOXMGGKEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104845   

TargetSodium/hydrogen exchanger 1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50104845(N-[2-(4-Fluoro-phenyl)-cyclopropanecarbonyl]-guani...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of NHE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50104845(N-[2-(4-Fluoro-phenyl)-cyclopropanecarbonyl]-guani...)
Affinity DataIC50: 1.60E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed