BDBM50104849 CHEMBL113201::N-(2-Phenyl-cyclopropanecarbonyl)-guanidine

SMILES NC(=N)NC(=O)[C@H]1C[C@@H]1c1ccccc1

InChI Key InChIKey=OKOXJPLBLDXQNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104849   

TargetSodium/hydrogen exchanger 1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50104849(N-(2-Phenyl-cyclopropanecarbonyl)-guanidine | CHEM...)
Affinity DataIC50: 500nMAssay Description:Inhibition of NHE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
University of South China

Curated by ChEMBL
LigandPNGBDBM50104849(N-(2-Phenyl-cyclopropanecarbonyl)-guanidine | CHEM...)
Affinity DataIC50: 3.50E+3nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed