BDBM50104972 2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2-hydroxy-indan-1-yl)-succinamide::CHEMBL115082

SMILES ONC(=O)C[C@@H](Cc1ccc2OCOc2c1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key InChIKey=PUKQZUALFZRFQE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104972   

TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed