BDBM50105012 4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(quinolin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-benzenesulfonamide; compound with GENERIC INORGANIC NEUTRAL COMPONENT::CHEMBL326160

SMILES COc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCOc2ccc3ccccc3n2)c1

InChI Key InChIKey=VKKQXEDQCUBPTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105012   

TargetEndothelin-1 receptor(Pig)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105012(4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(quinol...)
Affinity DataIC50: 15.2nMAssay Description:In vitro inhibition of [125I]ET1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed