BDBM50105037 4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(pyridin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-benzenesulfonamide::CHEMBL114105

SMILES COc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCOc2ccccn2)c1

InChI Key InChIKey=ZFQMMJJQAFLPQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105037   

TargetEndothelin-1 receptor(Pig)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105037(4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(pyridi...)
Affinity DataIC50: 8.80nMAssay Description:In vitro inhibition of [125I]ET1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed