BDBM50105247 6-Fluoro-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo[e][1,2]thiazine-3-carboxylic acid (1-benzyl-2-oxo-ethyl)-amide(3R,3S diastereomeric mixture)::CHEMBL331414

SMILES CN1C(Cc2cc(F)ccc2S1(=O)=O)C(=O)N[C@@H](Cc1ccccc1)C=O

InChI Key InChIKey=ISFKXYCVWVEOCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50105247   

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105247(6-Fluoro-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro-1la...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity towards human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105247(6-Fluoro-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro-1la...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against MOLT-4 cells (human T-cell leukemia cell line)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed