BDBM50105562 1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL327409

SMILES [O-][N+](=O)c1cccc(c1)-[c-]1ccc2nc(=[OH+])n(Cc3ccccc3)c2c1

InChI Key InChIKey=WKKRFUIAPXHJIZ-UHFFFAOYSA-O

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105562   

TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105562(1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimida...)
Affinity DataIC50: 62nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105562(1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimida...)
Affinity DataIC50: 257nMAssay Description:Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50105562(1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimida...)
Affinity DataKi:  714nMAssay Description:Binding affinity towards progesterone receptor was measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed