BDBM50105815 4-Allyl-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide::CHEMBL333210

SMILES OCCCN(c1ccnn1-c1ccccc1)S(=O)(=O)c1ccc(CC=C)cc1

InChI Key InChIKey=HEXQQYAWGOWNGP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105815   

TargetCytochrome P450 2C8(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105815(4-Allyl-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory effect on human recombinant liver Cytochrome P450 2C8 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105815(4-Allyl-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C9 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105815(4-Allyl-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105815(4-Allyl-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C19 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed