BDBM50105878 8-(3-Guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-11-(1H-indol-3-ylmethyl)-5-naphthalen-2-ylmethyl-3,6,9,12,17-pentaoxo-1,4,7,10,13pentaaza-cyclooctadecane-14-carboxylic acid amide::CHEMBL333262

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NCC(=O)CC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O

InChI Key InChIKey=SUMSUVXHWGYALM-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105878   

TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105878(8-(3-Guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-...)
Affinity DataEC50: >5.00E+3nMAssay Description:Increase in intracellular cAMP in CHO cells expressing human melanocortin receptor 5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105878(8-(3-Guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-...)
Affinity DataKi:  420nMAssay Description:Binding affinity against human melanocortin receptor 4 (hMC4R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105878(8-(3-Guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity against human melanocortin receptor 5 (hMC5R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105878(8-(3-Guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity against human melanocortin receptor 3 (hMC3R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed