BDBM50106110 CHEMBL98692::[1-(3-Methyl-3H-imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-(4-phenoxy-phenyl)-methanone

SMILES Cn1cncc1Cn1cc(C(=O)c2ccc(Oc3ccccc3)cc2)c(c1)-c1cccc2ccccc12

InChI Key InChIKey=CROAYTAFPRXEFL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106110   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Lgci

Curated by ChEMBL

LigandBDBM50106110([1-(3-Methyl-3H-imidazol-4-ylmethyl)-4-naphthalen-...)Copy SMILESCopy InChI

Affinity DataIC50: 4.60nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-ras protein by FarnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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