BDBM50106112 CHEMBL101889::[1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-(4-phenoxy-phenyl)-methanone

SMILES O=C(c1cn(Cc2cnc[nH]2)cc1-c1cccc2ccccc12)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=OLCYWDOABCSFNC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106112   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Lgci

Curated by ChEMBL

LigandBDBM50106112([1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-ras protein by FarnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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