BDBM50106494 7-Chloro-6-(2-morpholin-4-yl-ethylamino)-quinoline-5,8-dione::CHEMBL337520

SMILES Oc1c(Cl)c(N=CCN2CCOCC2)c(O)c2cccnc12

InChI Key InChIKey=QPIYLJBIUAHGPU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106494   

TargetM-phase inducer phosphatase 2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106494(7-Chloro-6-(2-morpholin-4-yl-ethylamino)-quinoline...)
Affinity DataIC50: 820nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106494(7-Chloro-6-(2-morpholin-4-yl-ethylamino)-quinoline...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Activity against Recombinant Human PTP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106494(7-Chloro-6-(2-morpholin-4-yl-ethylamino)-quinoline...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Activity against Recombinant Human VHRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50106494(7-Chloro-6-(2-morpholin-4-yl-ethylamino)-quinoline...)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant human NSD2 (941 to 1240 residues) using SAM as substrate incubated for 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed