BDBM50106499 6-Chloro-7-[2-(1H-indol-3-yl)-ethylamino]-quinoline-5,8-dione::CHEMBL340219

SMILES Oc1c(Cl)c(N=CCc2c[nH]c3ccccc23)c(O)c2ncccc12

InChI Key InChIKey=YDQFQLGMQJNASR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106499   

TargetM-phase inducer phosphatase 2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106499(6-Chloro-7-[2-(1H-indol-3-yl)-ethylamino]-quinolin...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106499(6-Chloro-7-[2-(1H-indol-3-yl)-ethylamino]-quinolin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Activity against Recombinant Human VHRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106499(6-Chloro-7-[2-(1H-indol-3-yl)-ethylamino]-quinolin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Activity against Recombinant Human PTP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50106499(6-Chloro-7-[2-(1H-indol-3-yl)-ethylamino]-quinolin...)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human NSD2 (941 to 1240 residues) using SAM as substrate incubated for 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed