BDBM50106855 3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL433159

SMILES COC(=O)C1C2CCC(CC1c1ccc(Br)cc1)N2CCCF

InChI Key

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106855   

TargetSodium-dependent dopamine transporter(Rat)
Alcohol and Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106855(3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...)
Affinity DataKi:  3.30nMAssay Description:Ability to displace [3H]- beta-CIT from Dopamine transporter in rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Alcohol and Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106855(3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...)
Affinity DataKi:  3.33nMAssay Description:Displacement of [3H]CIT from dopamine transporter of rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Alcohol and Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106855(3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...)
Affinity DataKi:  36nMAssay Description:Ability to displace [3H]- paroxetine from Serotonin transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Alcohol and Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106855(3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...)
Affinity DataKi:  36.4nMAssay Description:Displacement of [3H]cyanoimiprimine from serotonin transporter of rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Alcohol and Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106855(3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...)
Affinity DataKi:  196nMAssay Description:Ability to displace [3H]- nisoxetin from Norepinephrine transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Alcohol and Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106855(3-(4-Bromo-phenyl)-8-(3-fluoro-propyl)-8-aza-bicyc...)
Affinity DataKi:  196nMAssay Description:Displacement of [3H]-nisoxetine from norepinephrine transporter of rat cerebral corticex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed