BDBM50106903 CHEMBL3142817::{3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid

SMILES Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]2O)c(=O)n(CC(O)=O)c1=O

InChI Key InChIKey=QRBGBJXBTGHYMS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106903   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106903({3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataEC50:  1.80E+3nMAssay Description:Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106903({3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataIC50: 2.07E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 wild types GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106903({3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataIC50: 3.35E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed