BDBM50106947 Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid benzyl ester::CHEMBL104474

SMILES C=CCN(C1CCN(CCC(Cn2cnc3ccccc23)c2ccccc2)CC1)C(=O)OCc1ccccc1

InChI Key InChIKey=LMLXAFRSRSRFFX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106947   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106947(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: 25nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106947(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106947(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106947(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-X-C chemokine receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106947(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106947(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against C-C chemokine receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed