BDBM50106949 Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester::CHEMBL319622

SMILES CCc1nc2ccccc2n1CC(CCN1CCC(CC1)N(CC=C)C(=O)OCc1ccc(cc1)[N+]([O-])=O)c1ccccc1

InChI Key InChIKey=GJIXUOZRDMDHKV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50106949   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106949(Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-...)
Affinity DataIC50: 48nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106949(Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-X-C chemokine receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106949(Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106949(Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106949(Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against C-C chemokine receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106949(Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against C-C chemokine receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed