BDBM50107236 CHEMBL3600775

SMILES Nc1nc2ccc(cc2s1)-c1cnn(CC2CC2)c1

InChI Key InChIKey=SRNMYAZHFYKZCA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50107236   

TargetPhosphatidylinositol 4-kinase alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50107236(CHEMBL3600775)
Affinity DataIC50: 631nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length recombinant PI4K3alpha using D-myo-phosphatidylinositol substrate and ATP incubated for 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50107236(CHEMBL3600775)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50107236(CHEMBL3600775)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of N-terminal GST-tagged human full length recombinant PI4K3beta expressed in Sf9 cells using D-myo-phosphatidylinositol substrate and ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50107236(CHEMBL3600775)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50107236(CHEMBL3600775)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50107236(CHEMBL3600775)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed