BDBM50107275 CHEMBL3600690

SMILES Nc1nc2ccc(cc2s1)-c1ccc(CO)nc1

InChI Key InChIKey=GWFZHFIPPSSVCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107275   

LigandPNGBDBM50107275(CHEMBL3600690)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50107275(CHEMBL3600690)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50107275(CHEMBL3600690)
Affinity DataIC50: 794nMAssay Description:Inhibition of N-terminal GST-tagged human full length recombinant PI4K3beta expressed in Sf9 cells using D-myo-phosphatidylinositol substrate and ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50107275(CHEMBL3600690)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length recombinant PI4K3alpha using D-myo-phosphatidylinositol substrate and ATP incubated for 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed