BDBM50107485 CHEMBL345781::N-Biphenyl-3-ylmethyl-2-[2-(4-fluoro-benzylsulfanyl)-4-oxo-5-pyrimidin-5-ylmethyl-4H-pyrimidin-1-yl]-acetamide

SMILES Fc1ccc(CSc2nc(=O)c(Cc3cncnc3)cn2CC(=O)NCc2cccc(c2)-c2ccccc2)cc1

InChI Key InChIKey=PDXSKYLUKJUMAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107485   

TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107485(N-Biphenyl-3-ylmethyl-2-[2-(4-fluoro-benzylsulfany...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed