BDBM50107573 (2R)-2-[4-(1,3-benzodioxol-5-yl)benzyl]-N~4~-hydroxy-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide::(R)-2-(4-Benzo[1,3]dioxol-5-yl-benzyl)-N*4*-hydroxy-N*1*-((1S,2R)-2-hydroxy-indan-1-yl)-succinamide::CHEMBL8432

SMILES c1ccc2c(c1)C[C@H]([C@H]2NC(=O)[C@H](Cc3ccc(cc3)c4ccc5c(c4)OCO5)CC(=O)NO)O

InChI Key InChIKey=MJTVUROZTDIMFT-UHFFFAOYSA-N

Data  3 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107573   

Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharma

Curated by ChEMBL
LigandPNGBDBM50107573((2R)-2-[4-(1,3-benzodioxol-5-yl)benzyl]-N~4~-hydro...)
Affinity DataKi:  43nMAssay Description:Binding affinity for human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharma

Curated by ChEMBL
LigandPNGBDBM50107573((2R)-2-[4-(1,3-benzodioxol-5-yl)benzyl]-N~4~-hydro...)
Affinity DataKi:  309nMAssay Description:Binding affinity for human gelatinase B (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharma

Curated by ChEMBL
LigandPNGBDBM50107573((2R)-2-[4-(1,3-benzodioxol-5-yl)benzyl]-N~4~-hydro...)
Affinity DataKi:  1.28E+4nMAssay Description:Binding affinity for neutrophil collagenase (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed