BDBM50107623 CHEMBL140756::N-Cyanomethyl-2-diphenylacetylamino-3-m-tolyl-propionamide

SMILES Cc1cccc(C[C@H](NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NCC#N)c1

InChI Key InChIKey=SWPXTIFAGIZWNX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107623   

TargetProcathepsin L(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(N-Cyanomethyl-2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(N-Cyanomethyl-2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50: 87nMAssay Description:Inhibitory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(N-Cyanomethyl-2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50: 87nMAssay Description:Inhibitory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107623(N-Cyanomethyl-2-diphenylacetylamino-3-m-tolyl-prop...)
Affinity DataIC50: 88nMAssay Description:Inhibitory activity against recombinant human cathepsin S (cat S) expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed