BDBM50107629 3-[2-Cyano-2-(2-pentanoylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid::CHEMBL141793

SMILES CCCCC(=O)N[C@@H](Cc1cccc(C)c1)C(=O)N[C@@H](COCc1cccc(c1)C(O)=O)C#N

InChI Key InChIKey=VDRWKUPAXMUPEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107629   

TargetCathepsin B(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107629(3-[2-Cyano-2-(2-pentanoylamino-3-m-tolyl-propionyl...)
Affinity DataIC50: 35.7nMAssay Description:Inhibitory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107629(3-[2-Cyano-2-(2-pentanoylamino-3-m-tolyl-propionyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human cathepsin B expressed in baculovirus expression system using Z-Arg-Arg-AMC as substrate incubated for 20 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed