BDBM50107643 CHEMBL140824::N-[1-(Cyanomethyl-carbamoyl)-2-m-tolyl-ethyl]-2,4-difluoro-benzamide

SMILES Cc1cccc(C[C@H](NC(=O)c2ccc(F)cc2F)C(=O)NCC#N)c1

InChI Key InChIKey=GPDXFJXVSTUWRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107643   

TargetCathepsin B(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107643(N-[1-(Cyanomethyl-carbamoyl)-2-m-tolyl-ethyl]-2,4-...)
Affinity DataIC50: 591nMAssay Description:Inhibitory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed