BDBM50108034 5-[3-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-propyl]-benzo[1,3]dioxole-2-carboxylic acid ethyl ester::CHEMBL279062

SMILES CCOC(=O)[C@@H]1Oc2ccc(CCCn3ncc4c5nc(nn5c(N)nc34)-c3ccco3)cc2O1

InChI Key InChIKey=HLYUSSPLIJFDJS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108034   

TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50108034(5-[3-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  5.48nMAssay Description:Displacement of [3H]-SCH- 58261 from human Adenosine A2A receptor expressed in HEK293 cells; ranges from 4.95-6.08More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50108034(5-[3-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  1.79E+3nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cells; ranges from 1460-2201More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50108034(5-[3-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of specific [3H]MRE3008-F20 binding at human adenosine A3 receptor expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50108034(5-[3-(5-Amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of specific [3H]DPCPX binding at human adenosine A2B receptor expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed