BDBM50108132 CHEMBL75487::N-[2-(3'-Cyanomethyl-biphenyl-4-sulfonyl)-1-(4,4-dimethyl-2,5-dioxo-imidazolidin-1-ylmethyl)-ethyl]-N-hydroxy-formamide

SMILES CC1(C)NC(=O)N(CC(CS(=O)(=O)c2ccc(cc2)-c2cccc(CC#N)c2)N(O)C=O)C1=O

InChI Key InChIKey=IAPIGLKJGZQTIG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108132   

Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108132(N-[2-(3'-Cyanomethyl-biphenyl-4-sulfonyl)-1-(4,4-d...)
Affinity DataIC50: 0.350nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108132(N-[2-(3'-Cyanomethyl-biphenyl-4-sulfonyl)-1-(4,4-d...)
Affinity DataIC50: 0.910nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108132(N-[2-(3'-Cyanomethyl-biphenyl-4-sulfonyl)-1-(4,4-d...)
Affinity DataIC50: 78nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed