BDBM50108148 CHEMBL75464::N-{1-(2,2-Diethyl-[1,3]dioxolan-4-yl)-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-N-hydroxy-formamide

SMILES CCC1(CC)OCC(O1)[C@@H](CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)N(O)C=O

InChI Key InChIKey=PIPNMGRIVITFEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108148   

TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108148(N-{1-(2,2-Diethyl-[1,3]dioxolan-4-yl)-2-[4-(4-trif...)
Affinity DataIC50: 1.10nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108148(N-{1-(2,2-Diethyl-[1,3]dioxolan-4-yl)-2-[4-(4-trif...)
Affinity DataIC50: 20nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108148(N-{1-(2,2-Diethyl-[1,3]dioxolan-4-yl)-2-[4-(4-trif...)
Affinity DataIC50: 8.30E+3nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed