BDBM50108166 CHEMBL76043::N-[1-(5,5-Dimethyl-2,4-dioxo-imidazolidin-1-ylmethyl)-2-(4'-trifluoromethoxy-biphenyl-4-sulfonyl)-ethyl]-N-hydroxy-formamide

SMILES CC1(C)N(CC(CS(=O)(=O)c2ccc(cc2)-c2ccc(OC(F)(F)F)cc2)N(O)C=O)C(=O)NC1=O

InChI Key InChIKey=JGARQZXVQXLEJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108166   

TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108166(N-[1-(5,5-Dimethyl-2,4-dioxo-imidazolidin-1-ylmeth...)
Affinity DataIC50: 0.340nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108166(N-[1-(5,5-Dimethyl-2,4-dioxo-imidazolidin-1-ylmeth...)
Affinity DataIC50: 0.860nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108166(N-[1-(5,5-Dimethyl-2,4-dioxo-imidazolidin-1-ylmeth...)
Affinity DataIC50: 82nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed