BDBM50108175 5-(2-Methoxy-5-octyloxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL78648

SMILES CCCCCCCCOc1ccc(OC)c(Cc2cnc(N)nc2N)c1

InChI Key InChIKey=ALACOZSEHQPASW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108175   

TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108175(5-(2-Methoxy-5-octyloxy-benzyl)-pyrimidine-2,4-dia...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108175(5-(2-Methoxy-5-octyloxy-benzyl)-pyrimidine-2,4-dia...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108175(5-(2-Methoxy-5-octyloxy-benzyl)-pyrimidine-2,4-dia...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108175(5-(2-Methoxy-5-octyloxy-benzyl)-pyrimidine-2,4-dia...)
Affinity DataIC50: 4.40E+4nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed