BDBM50108191 3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22367

SMILES COc1ccccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1

InChI Key InChIKey=BOZMVLDNYMRJIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108191   

TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)
Affinity DataIC50: 310nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed