BDBM50108193 2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl-1H-indol-3-yl)-acetylsulfamoyl]-benzoic acid::CHEMBL278349

SMILES Cn1cc(C(C(=O)NS(=O)(=O)c2ccccc2C(O)=O)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O

InChI Key InChIKey=RDFPZCGBCKZXNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108193   

TargetEndothelin-1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)
Affinity DataIC50: 846nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed