BDBM50108451 1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-thiophen-2-yl-1H-pyridin-2-one::CHEMBL305339

SMILES O=c1c(cccn1C(CN1CCCC1)c1ccccc1)-c1cccs1

InChI Key InChIKey=MSHFBNAPZPBWBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108451   

TargetKappa-type opioid receptor(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108451(1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-thiophen-2-...)
Affinity DataIC50: 1.18E+3nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed