BDBM50108453 5-(3,4-Dichloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one::CHEMBL59924

SMILES Clc1ccc(cc1Cl)-c1ccc(=O)n(c1)C(CN1CCCC1)c1ccccc1

InChI Key InChIKey=KNGWWTVKCJNCAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50108453   

TargetKappa-type opioid receptor(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108453(5-(3,4-Dichloro-phenyl)-1-(1-phenyl-2-pyrrolidin-1...)
Affinity DataIC50: 1.49E+3nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed