BDBM50108708 1-(3-Phenylpropyl)-4-(phenylsulfonyl)piperidine::4-Benzenesulfonyl-1-(3-phenyl-propyl)-piperidine::CHEMBL148565

SMILES O=S(=O)(C1CCN(CCCc2ccccc2)CC1)c1ccccc1

InChI Key InChIKey=PZLOABUPAFZHAF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108708   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108708(4-Benzenesulfonyl-1-(3-phenyl-propyl)-piperidine |...)
Affinity DataKi:  15nMAssay Description:Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108708(4-Benzenesulfonyl-1-(3-phenyl-propyl)-piperidine |...)
Affinity DataKi: >1.50E+3nMAssay Description:Binding affinity for displacement of [3H]spiperone to human dopamine D2 (hD2) receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108708(4-Benzenesulfonyl-1-(3-phenyl-propyl)-piperidine |...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]-dofetilide to HEK cells stably expressing hERG voltage-gated IKr potassium channel Kv11.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108708(4-Benzenesulfonyl-1-(3-phenyl-propyl)-piperidine |...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed