BDBM50108709 1'-(2,4-difluorophenethyl)-6-fluorospiro[2H-chromene-2,4'-(hexahydropyridine)]::CHEMBL359270

SMILES Fc1ccc(CCN2CCC3(CC2)Oc2ccc(F)cc2C=C3)c(F)c1

InChI Key InChIKey=HTKIFNUUHOERMF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108709   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108709(1'-(2,4-difluorophenethyl)-6-fluorospiro[2H-chrome...)
Affinity DataKi:  16nMAssay Description:Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108709(1'-(2,4-difluorophenethyl)-6-fluorospiro[2H-chrome...)
Affinity DataKi:  650nMAssay Description:Binding affinity for displacement of [3H]spiperone to human dopamine D2 (hD2) receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed