BDBM50108845 CHEMBL436227::[1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarbamoyl)-3-methyl-butyl]-carbamic acid pyridin-4-ylmethyl ester

SMILES CC(C)C[C@H](NC(=O)OCc1ccncc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)CSC(C)(C)C

InChI Key InChIKey=JIMHQYPASLNACB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108845   

TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50108845([1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarb...)
Affinity DataKi:  14.1nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50108845([1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarb...)
Affinity DataKi:  28.8nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50108845([1-(1-Benzyl-3-tert-butylsulfanyl-2-oxo-propylcarb...)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibitory activity against human Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed