BDBM50108858 CHEMBL347459::{1-[2-Oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid pyridin-3-ylmethyl ester

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)C(=O)CSCCCc1ccccc1)OCc1cccnc1

InChI Key InChIKey=VZRKGDOTBQOIIT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108858   

TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50108858({1-[2-Oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50108858({1-[2-Oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50108858({1-[2-Oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-...)
Affinity DataKi:  28.8nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50108858({1-[2-Oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity against human Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed