BDBM50109476 1-(4-Bromo-phenyl)-3-(8-butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL350830

SMILES CCCCn1cc2c(n1)nc(NC(=O)Nc1ccc(Br)cc1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=BMCOYZDNAMZDPR-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50109476   

TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  0.910nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article

TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  0.910nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]MRE3008-F20 binding at human Adenosine A3 receptor expressed in HEK cells; range 0.82-1.02More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  0.910nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]SCH-58261 from human Adenosine A2A receptor expressed in HEK293 cells; range 47-93More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A2B receptor expressed in HEK293 cells; range 88-165More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 222-400More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109476(1-(4-bromophenyl)-3-(8-butyl-2-(furan-2-yl)-8H-pyr...)
Affinity DataKi:  912nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed