BDBM50109484 1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::1-Benzo[1,3]dioxol-5-yl-3-(8-butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::CHEMBL352192

SMILES CCCCn1cc2c(n1)nc(NC(=O)Nc1ccc3OCOc3c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=FCRUKTDNWPIBOC-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50109484   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]MRE3008-F20 from human Adenosine A3 receptor expressed in HEK cells; range 0.40-0.62More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  0.5nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  0.500nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article

TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A2B receptor expressed in HEK293 cells; range 57-105More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  376nMAssay Description:Displacement of [3H]SCH-58261 from human Adenosine A2A receptor expressed in HEK293 cells; range 332-426More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  376nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109484(1-(benzo[d][1,3]dioxol-5-yl)-3-(8-butyl-2-(furan-2...)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 314-536More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed