BDBM50109486 1-(3,4-Dichloro-phenyl)-3-(2-furan-2-yl-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL353299

SMILES CCCn1cc2c(n1)nc(NC(=O)Nc1ccc(Cl)c(Cl)c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=UBPNPYAOHJXLLA-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50109486   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]MRE3008-F20 from human Adenosine A3 receptor expressed in HEK cells; range 2.0-3.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  2.5nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A2B receptor expressed in HEK293 cells; range 25-40More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  401nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  401nMAssay Description:Displacement of [3H]SCH-58261 from human Adenosine A2A receptor expressed in HEK293 cells; range 362-445More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  611nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 552-676More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109486(1-(3,4-dichlorophenyl)-3-(2-(furan-2-yl)-8-propyl-...)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed