BDBM501095 (R)-7-((6- ((dimethylamino)- methyl)-5- (tetrahydrofuran- 3-yl)pyridin- 2-yl)amino)-4- (1H-pyrrolo[2,3- b]pyridin-4- yl)-2,3- dihydro-1H- pyrrolo[3,4- c]pyridin-1- one::US11021481, Compound I-767::US11078201, Compound I-767::US11548890, Compound I-767

SMILES CN(C)Cc1nc(Nc2cnc(c3CNC(=O)c23)-c2ccnc3[nH]ccc23)ccc1[C@H]1CCOC1

InChI Key InChIKey=ZUFVURKYVALPPA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 501095   

LigandPNGBDBM501095(US11021481, Compound I-767 | (R)-7-((6- ((dimethyl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM501095(US11021481, Compound I-767 | (R)-7-((6- ((dimethyl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM501095(US11021481, Compound I-767 | (R)-7-((6- ((dimethyl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM501095(US11021481, Compound I-767 | (R)-7-((6- ((dimethyl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM501095(US11021481, Compound I-767 | (R)-7-((6- ((dimethyl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent