BDBM50109528 CHEMBL3601115

SMILES COCCn1cc(Nc2ncc(Cl)c(NCc3cccc(NC(=O)C=C)c3)n2)cn1

InChI Key InChIKey=MTDJJMFQQXOEPJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50109528   

TargetTyrosine-protein kinase JAK3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109528(CHEMBL3601115)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of JAK3 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109528(CHEMBL3601115)
Affinity DataIC50: 407nMAssay Description:Inhibition of TYK2 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109528(CHEMBL3601115)
Affinity DataIC50: 51nMAssay Description:Inhibition of JAK2 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109528(CHEMBL3601115)
Affinity DataIC50: 35nMAssay Description:Inhibition of JAK1 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109528(CHEMBL3601115)
Affinity DataIC50: 212nMAssay Description:Inhibition of TTK (unknown origin) by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109528(CHEMBL3601115)
Affinity DataIC50: 43nMAssay Description:Inhibition of aurora-A (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed