BDBM50110179 CHEMBL190281

SMILES Brc1cc2cnc(Nc3ccc(cc3)N3CCNCC3)nc2n(C2CCCC2)c1=O

InChI Key InChIKey=PEOPNFFYHMAVJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110179   

TargetCyclin-dependent kinase 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110179(CHEMBL190281)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4 (unknown origin) using GST-fused pRb (792 to 928) as substrate preincubated for 2 mins followed by [gamma-32P]-ATP addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50110179(CHEMBL190281)
Affinity DataIC50: 43nMAssay Description:Inhibition of CDK2 (unknown origin) using GST-fused pRb (792 to 928) as substrate preincubated for 2 mins followed by [gamma-32P]-ATP addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed